The Powerpuff Girls face their greatest challenge in this 10th anniversary special episode. There exists a Key to the World, which is handed from city to city on an annual basis. Whoever possesses the key rules over the entire world. When the key is delivered to Townsville, every villain in Townsville attempts to retrieve it. When the girls procure it for themselves, they quickly get sucked into a power struggle, fighting the villains and themselves over who gets to rule the world.

Genres

Cast

Cathy Cavadini

Blossom (voice)

Tara Strong

Bubbles / Alarm System (voice)

E. G. Daily

Buttercup (voice)

Tom Kenny

Narrator / Mayor / Dove (voice)

Tom Kane

Professor / Him / Talking Dog (voice)

Roger L. Jackson

Mojo Jojo (voice)

Jennifer Martin

Ms. Bellum (voice)

Kevin Michael Richardson

Fish Balloon (voice)

Jeff Bennett

Ace / Prisoner / Concerned Citizen (voice)

Jim Cummings

Fuzzy Lumpkins (voice)

Jennifer Hale

Princess (voice)